Microbiome refers to the collection of microorganisms that inhabit not only the gut, but also the skin, respiratory tract, mucous membranes, urogenital system, and even the surrounding environment. The human body contains more microbial cells than human cells: for every human cell, there are about 1.3 microbial cells. The total mass of the microbiome is 1.5–2 kg, and its genes outnumber human genes by a factor of 150.
Methylation is a crucial biochemical process occurring in all cells of the body. It involves adding a methyl group (CH₃) to molecules such as DNA, proteins, and lipids, significantly influencing their functions and activities. Methylation regulates various physiological mechanisms, including gene expression, detoxification, mood regulation, energy production, immune system function, and cellular maintenance. Particularly important is the role of methylation in the liver, where it helps neutralize and eliminate toxins, which is essential for overall health.
