SIBO

Bifidobacteria are one of the key representatives of the normal gut microbiota, playing an important role in maintaining overall health. They colonize the intestines from the first days of life and participate in numerous processes that support digestion, strengthen the immune system, and synthesize essential vitamins.

However, with age and under the influence of various factors, their numbers decrease, leading to microbial imbalance and increasing the risk of various diseases. Understanding the distribution of bifidobacteria in the gut, their functions, and the factors that affect their levels helps maintain microbiome balance and prevent potential health problems.

For effective treatment of dysbiosis, it is crucial to begin with accurate diagnostics. In the first article, we discussed the basic concepts of dysbiosis, its impact on health, and potential causes. Many health conditions may present with similar symptoms but require different treatment approaches. As mentioned earlier, dysbiosis-related issues can be identified using a variety of diagnostic methods. The primary ones are stool analysis and breath tests. Stool analysis can detect the presence of pathogenic bacteria, viruses, and fungi, while breath tests effectively reveal carbohydrate fermentation disorders, which may indicate SIBO (small intestinal bacterial overgrowth).

Gut Microbiota is a complex ecosystem of microorganisms, including bacteria, viruses, fungi, and parasites, that inhabit the human intestinal tract. The number of microbes in the human body is estimated to be around 39 trillion, slightly exceeding the number of human cells. However, their genetic material is much richer and has a profound impact on bodily functions.

The microbiota performs many key functions, such as aiding digestion, synthesizing vitamins, protecting against pathogens, and supporting the immune system. A healthy microbiota is key to maintaining long-term health, whereas imbalances may trigger a wide range of diseases.

The second part of the article focuses on the diagnosis of Small Intestinal Bacterial Overgrowth (SIBO), continuing the discussion of essential topics not covered in Part One. In that part, we reviewed the core symptoms and causes of SIBO. Now we focus on diagnostic tools that help identify this condition and guide optimal therapy. Distinguishing between the different types of SIBO — hydrogen, methane, and hydrogen sulfide — requires accurate diagnostic methods to select the correct treatment. Importantly, diagnosing SIBO not only confirms the condition but helps rule out other diseases with similar symptoms.

SIBO (Small Intestinal Bacterial Overgrowth) is a condition where bacteria that are normally present in small amounts in the small intestine—or that typically reside in the large intestine—begin to proliferate in the small intestine. SIBO disrupts normal digestion and nutrient absorption.

Symptoms of SIBO include bloating, abdominal pain, diarrhea, or constipation. However, it’s not just discomfort—SIBO can significantly impact quality of life, leading to chronic fatigue, skin issues, weight loss, and vitamin and mineral deficiencies. The underlying cause of SIBO is often another condition, and SIBO is a dysfunction of the gut that results from this primary issue.

Methylation is a crucial biochemical process occurring in all cells of the body. It involves adding a methyl group (CH₃) to molecules such as DNA, proteins, and lipids, significantly influencing their functions and activities. Methylation regulates various physiological mechanisms, including gene expression, detoxification, mood regulation, energy production, immune system function, and cellular maintenance. Particularly important is the role of methylation in the liver, where it helps neutralize and eliminate toxins, which is essential for overall health.