MCAS

Imagine someone starts noticing strange, seemingly unrelated symptoms. After a glass of wine — a sudden hot flush, nasal congestion, and a feeling of an oncoming cold. A bit of aged cheese — itching, heaviness in the stomach, bloating. After eating strawberries — a rash that disappears without a trace in a couple of hours.

In the morning — a dull headache “out of nowhere.” Throughout the day — bouts of irritability and anxiety. In the evening — insomnia and restless sleep. Sometimes after eating — a wave of fatigue so strong it feels like the body is “shutting down.” During stress or certain phases of the hormonal cycle — abdominal pain intensifies, dark thoughts appear, only to be suddenly replaced by a burst of energy and hyperactivity.

Multisystem chronic conditions are disorders in which multiple body systems—such as the nervous, vascular, digestive, musculoskeletal, and immune systems—are affected simultaneously. Symptoms can range widely, from dizziness and pain to digestive issues and persistent fatigue.

When the body is exposed to mycotoxins, it’s crucial not only to eliminate the source of mold but also to support the body’s recovery. Nutrition plays a central role in reducing toxic load.

A properly designed diet can help reduce inflammation, support liver and gut function, enhance toxin elimination, and significantly ease symptoms such as fatigue, brain fog, food reactivity, and poor tolerance to other therapies — from binders to nutritional supplements.

In medical education, emphasis is placed on the ability to think about the most likely causes of illnesses, referred to as “horses” rather than rare cases, or “zebras”. This helps to diagnose common problems more quickly, but often leads to the overlooking of rare conditions. Therefore, the symbol of rare diseases, such as Ehlers-Danlos syndrome, is a zebra — to remind doctors of the importance of considering unusual cases. Now,Hugo let’s talk about this and other “zebras”.

Mast Cell Activation Syndrome (MCAS) is a chronic condition in which mast cells in the body become excessively activated. This leads to the release of numerous chemical substances that can cause diverse symptoms affecting various systems of the body.

Hypermobility is a condition where joints have greater flexibility than usual. People with hypermobility can bend and extend their joints beyond normal ranges of motion. So far, this doesn’t sound too bad, right? Moreover, we usually envy people with hypermobility; after all, they can easily do splits, whereas an average person might need weeks, if not months, of training. Indeed, this condition can be harmless and even advantageous in certain sports and activities, such as gymnastics and dance, but it can also lead to various medical issues.

Postural Orthostatic Tachycardia Syndrome (POTS) is often a puzzling condition, the causes of which can be extremely difficult to pinpoint, and it can significantly incapacitate individuals.